Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 724024
Gene Symbol: MIR654
MIR654
0.010 Biomarker disease BEFREE MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654. 31608058 2019
Entrez Id: 2833
Gene Symbol: CXCR3
CXCR3
0.010 Biomarker disease BEFREE CXCR3+CCR6-Tph (Tph1) cells were expanded in the SLE patients. 31180450 2019
Entrez Id: 6271
Gene Symbol: S100A1
S100A1
0.010 AlteredExpression disease BEFREE There were no significant differences in S100 levels between the iSLE and SLE patients. 30392117 2019
Entrez Id: 6019
Gene Symbol: RLN2
RLN2
0.010 Biomarker disease BEFREE Human recombinant relaxin-2 does not attenuate hypertension or renal injury but exacerbates vascular dysfunction in a female mouse model of SLE. 31125285 2019
Entrez Id: 2152
Gene Symbol: F3
F3
0.010 GeneticVariation disease BEFREE SLE NETs were decorated with tissue factor (TF) and interleukin-17A (IL-17A), which promoted thrombin generation and the fibrotic potential of cultured skin fibroblasts. 30563869 2019
Entrez Id: 4810
Gene Symbol: NHS
NHS
0.010 Biomarker disease BEFREE Changing trends in mortality in systemic lupus erythematosus? An analysis of SLE inpatient mortality at University Hospital Coventry and Warwickshire NHS Trust from 2007 to 2016. 31570977 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.010 AlteredExpression disease BEFREE After adjustment for multiple comparisons, GCF levels of interleukin (IL)-1β, IL-8, granulocyte colony-stimulating factor (G-CSF), interferon-γ and monocyte chemoattractant protein-1 were significantly higher, whereas the levels of granulocyte-macrophage colony-stimulating factor were significantly lower in jSLE patients. 30563424 2019
Entrez Id: 8482
Gene Symbol: SEMA7A
SEMA7A
0.010 AlteredExpression disease BEFREE No differences in plasma Sema3A and Sema7A levels were detected in SLE patients of different genotypes. 31394943 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
0.010 AlteredExpression disease BEFREE Excessive miR-152-3p Results in Increased BAFF Expression in SLE B-Cells by Inhibiting the KLF5 Expression. 31178864 2019
Entrez Id: 9987
Gene Symbol: HNRNPDL
HNRNPDL
0.010 Biomarker disease BEFREE SLE anti-BC abs effectively compete with RNA transport factor heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) for DTE access and significantly diminish BC RNA delivery to synapto-dendritic sites of function. 31405929 2019
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
0.010 Biomarker disease BEFREE This study investigated the expression of vascular adhesion protein-1 (VAP-1) in SLE patients with conjunctivitis and the relationship between VAP-1 and other proteins in the onset of the disease. 31819770 2019
Entrez Id: 55937
Gene Symbol: APOM
APOM
0.010 AlteredExpression disease BEFREE Since apoM plasma levels decrease during inflammatory conditions, our aim was also to determine the impact of SLE disease activity on apoM plasma levels. 31046824 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
0.010 Biomarker disease BEFREE Association between the ratio of aryl hydrocarbon receptor (AhR) in Th17 cells to AhR in Treg cells and SLE skin lesions. 30743201 2019
Entrez Id: 1840
Gene Symbol: DTX1
DTX1
0.010 AlteredExpression disease BEFREE In addition, low DTX1 expression in SLE patients was associated with active LN, lung involvement or hypocomplementaemia. 30629240 2019
Entrez Id: 80231
Gene Symbol: CXorf21
CXorf21
0.010 Biomarker disease BEFREE Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis. 31695690 2019
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.010 AlteredExpression disease BEFREE SLE LDG exhibited significantly heightened surface expression of various activation markers and also of lectin-like oxidised low-density lipoprotein receptor-1, previously described to be associated with PMN-MDSC. 31040119 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 Biomarker disease BEFREE Relationship assessment and fatigue severity scale scores were found to be the best indicators of depression for the SLE patients (P = .042 and .028, respectively).Fatigue Severity, relationship satisfaction, and IL-10 concentrations are indicators of depression in lupus patients. 29995777 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.090 GeneticVariation disease BEFREE Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. 30171347 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker disease BEFREE Urinary neutrophil gelatinase-associated lipocalin and monocyte chemoattractant protein 1 as biomarkers for lupus nephritis in Colombian SLE patients. 29073812 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.060 Biomarker disease BEFREE The <i>STAT4</i> SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE. 29475858 2018
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.050 Biomarker disease BEFREE β regulatory subunit of PP2A regulates IL-2 deprivation-induced T cell death and is decreased in SLE patients. 28736280 2018
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
0.040 GeneticVariation disease BEFREE Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. 30171347 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.030 AlteredExpression disease BEFREE SLE disease activity and complement components may suggest regulatory effect of adipokines (adiponectin and leptin) on disease pathogenesis. 30098476 2018
Entrez Id: 7292
Gene Symbol: TNFSF4
TNFSF4
0.030 Biomarker disease BEFREE OX40L/OX40 axis impairs follicular and natural Treg function in human SLE. 30568041 2018
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
0.030 Biomarker disease BEFREE Previous studies have reported that genes relating to JAK-STAT pathway (IFIH1, TYK2 and IL-10) conferred the susceptibility to SLE. 30171347 2018